Basilica of the Holy Cross in Jerusalem

Early Roman houses dating back to the 1st century, believed to be homes of early Christians. Well-preserved frescoes and a small museum.

This is the island located in the middle of the Tiber River (Il Fiume Tevere) that separates Central Rome and Trastevere. It boasts both a major hospital, called Fatebenefratelli, and a small synagogue that was secretly used in the Second World War when Rome's main synagogue nearby was closed down. It also has a café and gelateria on the Rome side. It is a nice way of getting to and from Trastevere. Be sure to get photos from Ponte Garibaldi as Isola Tiberina truly is beautiful. The island is 270 m long and up to 67 m broad. According to the legend envoys were sent to the temple of Asklepius in Epidauros in Greece in 291BC in order to get relief from an epidemic in Rome. The envoys brought one of the holy snakes back with them. The snake swam to the Tiber Island thus determining the place where a temple for Asklepius was built. The successor of the Asklepius sanctuary is the Church San Bartolomeo which was built by the German Emperor Otto III around the year 1000. The Ponte Rotto is what is left from the ancient Pons Aemilius, the oldest stone bridge over the Tiber erected around 180 BC. The bridge was partly destroyed during a flood in 1557, re-erected by Pope Gregor XIII and finally pulled down in 1598. In 62 BC the Senatorial road construction office replaced the wooden footbridge by the Ponte Fabricio.

A 19th-century addition to the square, made to balance the Fontana del Moro.

An example of urban planning that goes back to Pope Julius II, who, in 1508, envisioned it as a street that would connect all major government buildings. It is around a kilometer long and is in a straight line, an unusual feature for the time. It is lined with some interesting palaces but these days is more known for its antique shops. Via Giulia runs parallel with and one block from the River Tiber.

This building housed the University of Rome from the middle of the 15th century until 1935. The splendid interior courtyard was created by Giacomo della Porta. The inside church of Sant'Ivo (see above) is one of the masterpieces of the architect Borromini.

This palace of the 16th century was erected by the famous Medici family. It was the residence of Cardinals Giovanni and Giuliano Medici, later Pope Leo X. and Clement VII. Catherine de Medici, Pope Clement VII's niece lived here until her marriage in 1553 with Prince Henry, the son of King Francis I of France. The palace is named after Madama Margerita of Austria, the illegitimate daughter of Emperor Charles V. Since 1871 it has been the seat of the Italian Senate.

The Collegio Romano was a college of the Jesuit order. Many popes, cardinals and bishops were educated here. Since 1870 it has been a secular (non-monastic) school. The coat of arms on the doorway is that of Pope Gregory XIII (1572–1585). The tower was erected in 1787 and served as an observatory. Until 1925 all clocks in Rome were set after that of the Collegio Romano.

One of Bernini's masterpieces, an obelisk on the back of an elephant.

Built in the 17th century to a design based on an architectural sketch by Michelangelo. Highlights include the ancient Colossus of Constantine statue (the Colosseum was probably named for another giant statue, the Colossus of Nero which stood near the Flavian Amphitheatre as the Colosseum was originally known), The Dying Gaul, a magnificent marble sculpture that copies a bronze Greek original of the 3rd century BC and the Capitoline Venus. It also contains the remarkable original gilt bronze equestrian statue of emperor Marcus Aurelius (the one in the piazza is a replica).

An ethnographic collection of around 60,000 pieces from European indigenous cultures. Documents evolution from the Palaeolithic age to the Iron Age.

Perhaps the most fascinating building in Rome. The core of the structure began life as the mausoleum of Emperor Hadrian, built between 135 and 139 AD. Subsequent strongholds built on top of the mausoleum were in turn incorporated into a residence and castle by medieval Popes. The building was used as a prison until 1870 but now houses a museum. Opera buffs will be exhilarated to visit the balcony from which Tosca leaps to her death. Film buffs will recognise it as a setting from Angels and Demons.

The enormous building at the southeast end of the Circus Maximus is the headquarters of the UN Food and Agriculture Organization (FAO). From its roof are undoubtedly the best views of Rome, but you will need to know someone who works there to get past the strict security.

Also based on a Michelangelo architectural plan, this compact gallery is well endowed in classical sculpture and paintings. Highlights include the small 1st-century-BC bronze Lo Spinario, a Greek statue of a little boy picking a thorn from his foot; the Lupa Capitolina (Capitoline Wolf), a rare Etruscan bronze statue probably dating from the 5th century BC; and (in the entrance courtyard), the massive head, hands, foot and kneecap from a colossal statue of Constantine the Great. The palace also contains a Pinacoteca (Picture Gallery) with paintings mainly from the 16th and 17th centuries - highlights include: Caravaggio's Fortune-Teller and his curious John the Baptist; The Holy Family, by Dosso Dossi; Romulus and Remus, by Rubens; and Titian's Baptism of Christ.

Erected in 203. You can see it close up from Via della Curia also (without entering the Forum).

Built in 141 AD and dedicated to the Empress Faustina; after her husband emperor Antoninus Pius died in 161 AD the temple was rededicated to the couple.

They are posted at entrances to the Vatican City to provide security and protect the Pope. They wear very colourful clothing, similar to the uniforms worn by Renaissance-era soldiers. The Pontifical Swiss Guards is also the smallest and oldest standing army in the world, founded in 1506 by Pope Julius II. The origins of the Swiss guards, however, go back much further as the popes had regularly imported Swiss mercenaries during the 1400s.

Brand new museum designed to celebrate the art and architecture of the 21st century.