Four Rivers Fountain

This is not the real name of the church on the corner by the main entrance to San Callisto but it is universally known by this name. By legend it is located on the spot where Saint Peter had a vision of the risen Christ while fleeing persecution in Rome. According to the tradition, Peter asked Jesus, Domine, quo vadis? “Lord, where are you going?” The current church is from 1637. Inside is a copy of a stone said to contain the imprints of the feet of Jesus; the original is maintained in San Sebastiano, further along the Appian Way

Delightful Renaissance house that was built by a rich banker from Siena, Agostino Chigi. In 1577 it was bought by the Farnese family and has since been known as Villa Farnesina. At one time there were plans by Michelangelo to build a bridge over the river to connect the villa with Palazzo Farnese on the other side. You can tour several beautiful rooms that are all decorated with frescoes, including some by Raphael. Particularly entertaining is the Loggia of Cupid and Psyche, the former entrance hall, in which nearly every person represented is without clothes.

Contains the ruins of several large villas that belonged to wealthy Roman families. You can buy a combined ticket for the Palatine Hill, the Roman Forum and the Colosseum here, avoiding the long lines at the Colosseum. While the Imperial and Roman Fora are probably more spectacular, overall, there are amazing sights on the Palatine Hill, so unless you are terribly short on time or find it too challenging to climb the hill, allow an hour or more for these sights, too.

housed in the baroque palace Corsini where Christina, Queen of Sweden settled down in the last years of her life

This is the island located in the middle of the Tiber River (Il Fiume Tevere) that separates Central Rome and Trastevere. It boasts both a major hospital, called Fatebenefratelli, and a small synagogue that was secretly used in the Second World War when Rome's main synagogue nearby was closed down. It also has a café and gelateria on the Rome side. It is a nice way of getting to and from Trastevere. Be sure to get photos from Ponte Garibaldi as Isola Tiberina truly is beautiful. The island is 270 m long and up to 67 m broad. According to the legend envoys were sent to the temple of Asklepius in Epidauros in Greece in 291BC in order to get relief from an epidemic in Rome. The envoys brought one of the holy snakes back with them. The snake swam to the Tiber Island thus determining the place where a temple for Asklepius was built. The successor of the Asklepius sanctuary is the Church San Bartolomeo which was built by the German Emperor Otto III around the year 1000. The Ponte Rotto is what is left from the ancient Pons Aemilius, the oldest stone bridge over the Tiber erected around 180 BC. The bridge was partly destroyed during a flood in 1557, re-erected by Pope Gregor XIII and finally pulled down in 1598. In 62 BC the Senatorial road construction office replaced the wooden footbridge by the Ponte Fabricio.

Four fountains from the time of Pope Sixtus V when much of Rome was redeveloped. A reclining deity is the theme of each sculpture. This is a busy intersection and if you don't look twice you may miss these exquisite examples of Roman mythology.

This is one of the two main Jesuit churches in Rome, the other being the nearby Sant'Ignazio. The interior is Baroque art on steroids. Simply astounding.

Contains the tomb of Pope Hadrian IV, the last non-Italian pope before Pope John Paul I.

A truly monumental stairway of 135 steps (similar to climbing eight flights of stairs), built with French funds between 1721 and 1725 in order to link the Bourbon Spanish embassy to the Holy See (still located in the piazza below), with the Bourbon French church (its monastery founded in 1495) above. Don't sit on them though, or eat, or push a baby stroller on them, or do anything else that might obstruct pedestrians, make them dirty, or cause additional wear and tear, or else you will have to pay a fine that ranges from €250 to €400.

This garden was established in 1883. It has over 3,500 species of plants and includes a "Scent-and-Touch" garden for those who are visually impaired.

Also based on a Michelangelo architectural plan, this compact gallery is well endowed in classical sculpture and paintings. Highlights include the small 1st-century-BC bronze Lo Spinario, a Greek statue of a little boy picking a thorn from his foot; the Lupa Capitolina (Capitoline Wolf), a rare Etruscan bronze statue probably dating from the 5th century BC; and (in the entrance courtyard), the massive head, hands, foot and kneecap from a colossal statue of Constantine the Great. The palace also contains a Pinacoteca (Picture Gallery) with paintings mainly from the 16th and 17th centuries - highlights include: Caravaggio's Fortune-Teller and his curious John the Baptist; The Holy Family, by Dosso Dossi; Romulus and Remus, by Rubens; and Titian's Baptism of Christ.

Pope Sixtus IV della Rovere (1471-1481) gave order to replace the old Roman bridge by a new one. It was Pope Sixtus IV who also ordered the Sistine Chapel and the Opsedale di Santo Spirito to be built. So he ran out of money. He levied a tax on prostitution in order to gain money for the construction of the Ponte Sisto.

One of the most splendid (still private) Baroque grand palaces in Rome.

The first pedestrian-only bridge was built here in 206 BC and marks the passage of the Roman Via Flaminia over the Tiber. In 115 BC, the original bridge was demolished and rebuilt. It has been restored and remodelled several times since. In 2006, the bridge began attracting couples who, influenced by a movie, used a lamppost on the bridge to hang padlocks as a sign of their love, locking the padlock to the lamppost, then throwing the key behind them into the river. In 2007 the lamppost collapsed under the weight! Feeling sorry for the lovers the mayor ordered construction of steel posts, where padlocks can once again be hung.

A 1st-century tomb surrounded by two farmhouses from the Middle Ages, one of which used to be a cheese store. Rather hidden behind a high wall, the tomb is rarely open to the public. You might be lucky on a Sunday: on the third Sunday of every month there is a guided tour at 11:00.

Casal Rotondo is the biggest mausoleum on the Appian Way, at about the sixth mile. It now incorporates a small private villa, originally a farmhouse. It is not known for whom it was built. The wall of fragments next to it, constructed by Luigi Canina, has ruins referring to the Cotta family but this family is now believed to not be associated with the Casal Rotondo.

On the other side of the Via dei Fori Imperiali to the Roman Forum. Well-preserved market area that doubled as a way of stopping the Quirinal Hill from collapsing. Below in the Forum is Trajan's Column, built in 113 with reliefs depicting the Emperor Trajan's vistories in battle.

This church was built next to the mausoleum of Santa Costanza in the 7th Century and is on top of catacombs. It is very unusual in that the floor level is at the level of the catacomb floor, and the street entrance is at the level of the second floor gallery. The body of St. Agnes lies in a silver sarcophagus. There are several stories about her death at the age of 13 in 304 AD. One is that the prefect Sempronius wanted her to marry his son, and condemned her to death when she refused. Roman law did not permit the execution of virgins, so he ordered her to be raped but her virginity was miraculously preserved. She was then condemned to be burnt at the stake but the wood would not burn. Another is that she was stripped naked by the Emperor Diocletian because of her refusal to marry but that her hair then grew rapidly to preserve her modesty.

Erected in 203. You can see it close up from Via della Curia also (without entering the Forum).